Mitochondrial dysfunction in children with autism spectrum disorder - Dr. Richard Frye
Posted by Mike Healy
On May 27, 2014, 10:51 am
Mitochondrial dysfunction a prevalent metabolic abnormalities in autism spectrum disorder (ASD), yet it remains poorly understood. We examined mitochondrial function in immune cell lines and fresh immune cells derived from ASD children. A significant subgroup of immune cells had mitochondrial which became dysfunctional when exposed to reactive oxygen species. These data supports the presence of a unique metabolic endophenotype of ASD children with relatively worse developmental outcomes.
